Crack the Code to GLP-1: Real Solutions for Real Metabolic Healing
May 09, 2025
GLP-1: What It Is, What It Does, and How to Boost It Naturally
If you’ve heard of Ozempic®, Wegovy®, or Mounjaro™, you’ve heard about GLP-1. But what exactly is it—and why is it getting so much attention? More importantly, how can you work with your body—whether you’re using a GLP-1 medication or not—to build true, lasting metabolic resilience?
Let’s explore the science of GLP-1, how these medications work, the risks and benefits….
What Is GLP-1?
GLP-1 stands for Glucagon-Like Peptide-1, a hormone naturally produced in the gut in response to food. It plays a crucial role in metabolic health by:
- Balancing blood sugar after meals
- Stimulating insulin secretion
- Slowing gastric emptying, keeping you fuller longer
- Reducing appetite and cravings
This makes it a key player in both diabetes management and weight regulation.
Why GLP-1 Production Can Be Disrupted in the Gut?
GLP-1 is primarily produced by special cells in the small intestine known as L-cells. These cells are sensitive to your diet, gut microbiome, inflammation levels, and even stress. When the gut environment is compromised, GLP-1 production can decline, impacting your appetite regulation, blood sugar control, and metabolism.
Here are some key reasons why GLP-1 production may be impaired:
- Chronic Inflammation: Inflammation in the gut—often triggered by processed foods, sugar, poor sleep, and stress—can damage the delicate lining of the intestines where GLP-1 is produced. This results in reduced GLP-1 secretion and increased insulin resistance.
- Gut Dysbiosis: An imbalanced gut microbiome (too many harmful bacteria, not enough beneficial ones) can interfere with signaling between gut cells and hormones like GLP-1. This results in a weaker hormone response after eating and increased cravings.
- Low-Fiber, High-Sugar Diets: GLP-1 is naturally stimulated by nutrients like fiber and healthy fats. Diets high in sugar and refined carbs reduce microbial diversity and don’t properly stimulate GLP-1 production. This results in reduced appetite control and increased blood sugar spikes.
- Frequent Snacking or Overeating: Constant eating—especially highly processed foods—can blunt the body’s hormonal response, including GLP-1.This results in the body becoming less responsive to its own appetite and satiety signals (hormones).
- Aging & Hormonal Shifts: As we age (especially through perimenopause and menopause), changes in estrogen, testosterone, and insulin sensitivity can reduce the gut’s ability to produce GLP-1 effectively. This results in increased fat storage, cravings, and slower metabolism.
- Sedentary Lifestyle: Movement actually enhances gut hormone signaling, including GLP-1. A lack of regular physical activity can weaken GLP-1 responses.
This results in lower energy, poor glucose control, and appetite dysregulation.
The Good News?
All of these triggers are modifiable. That’s why programs like Phil’s 30 Day REBOOT works so well—it is designed to reduce inflammation, rebalance the microbiome, and reignite your natural GLP-1 production through targeted nutrition, movement, and sustainable self-care.
GLP-1 Medications: Benefits & Considerations
Drugs like Ozempic®, Wegovy®, Rybelsus®, and Mounjaro™ are synthetic GLP-1 receptor agonists. They mimic the body’s natural GLP-1 hormone and are prescribed to treat type 2 diabetes or aid in weight loss.
Potential Benefits:
- Improved glycemic control
- Reduced hunger and food intake
- Clinically significant weight loss
Potential Risks & Side Effects:
- Nausea, vomiting, constipation, diarrhea
- Muscle loss (especially without adequate protein or exercise)
- Gallbladder issues or pancreatitis (rare but serious)
- Fatigue, dehydration, or dizziness
Long-term metabolic effects are still under research!!!!!
It is important to mention that these medications do not replace healthy habits—they work best with them. In fact, without supportive lifestyle changes, benefits often diminish over time or reverse when the medication is stopped.
Why Muscle Loss Matters—Especially During Rapid Weight Loss
One of the most important things to understand about weight loss, especially when it happens quickly, or when you’re using medications like GLP-1 agonists (e.g., Ozempic® or Wegovy®)—is that not all the weight you lose is fat. A significant portion can come from lean muscle mass, and that’s something we want to preserve, not lose.
So why is muscle so important?
Muscle isn’t just for strength or appearance. It’s actually one of your body’s most powerful metabolic tools.
Here's why…
Muscle Supports a Healthy Metabolism
Muscle is “metabolically active” tissue, meaning it burns calories—even when you’re resting. The more lean muscle you have, the more energy your body uses throughout the day.
Lose muscle = lower metabolism = easier to regain weight.
Muscle Protects Hormonal and Blood Sugar Balance
Muscle acts like a sponge for blood sugar, helping keep glucose levels steady and preventing spikes and crashes that lead to cravings and fatigue.
When you lose muscle, your body becomes more insulin resistant and less efficient at managing energy.
Muscle Is Critical as We Age
As we get older—especially through menopause or andropause—we naturally lose muscle mass. This process is called sarcopenia, and it can accelerate dramatically if we aren’t proactive with nutrition and strength training.
More muscle = better aging, more energy, less risk of falls or frailty.
GLP-1 Medications + Low Appetite = Risk of Undereating
Many people on GLP-1 medications find their appetite drops significantly. While this may feel like a “win” for weight loss, it can also lead to inadequate protein intake—which puts lean muscle at risk.
If your body isn’t getting enough protein (or calories), it may start breaking down muscle tissue for energy, especially during rapid weight loss.
How to Protect Your Muscle While Losing Weight
Losing weight isn’t just about seeing a smaller number on the scale. The real goal? Lose fat while keeping—or even building—lean muscle. Muscle helps protect your metabolism, gives you energy, and supports long-term health.
Here’s how to make that happen:
Step 1: Prioritize Protein
Protein is essential for preserving muscle, balancing hormones, managing cravings, and supporting recovery.
General Protein Guidelines:
Most women: 80–100 grams per day
Most men: 100–130 grams per day
On GLP-1 meds or very active? Aim for 1.2–1.6 grams per kg of body weight.
For example:
A 150 lb woman = 82–109 grams/day
A 180 lb man = 98–131 grams/day
Pro Tip: Spread protein out during the day—25–30 grams per meal helps fuel your muscles and stabilize energy levels, especially when your appetite is lower.
Step 2: Build Strength with Resistance Training
To keep muscle while you lose fat, your body needs to use those muscles!
Aim for 2–4 strength-focused sessions per week
This could include bodyweight exercises, resistance bands, free weights, or strength-based fitness classes. Muscle is metabolically active tissue—more muscle means a faster metabolism and better long-term results.
Step 3: Nourish with Whole Foods and Hydration
- Stay well hydrated to support digestion and muscle recovery
- Choose nutrient-dense, anti-inflammatory foods—not just fewer calories
- Focus on fueling your body, not depriving it
Weight loss through starvation leads to fatigue and rebound weight gain. Nourishment builds resilience, energy, and true health.
Why Phil’s 30 Day REBOOT Makes This Easy
Philippa’s REBOOT isn’t just about losing weight—it’s about nourishing and rebuilding your body from the inside out. Every phase of the REBOOT supports lean muscle with:
- Protein-forward, anti-inflammatory meals
- High-protein snacks and smoothies
- A sustainable movement mindset that fits real life
Whether you're on GLP-1 medication or simply ready for a metabolism reset, the REBOOT helps you protect what matters most—your muscle, your strength, and your long-term health.
CAN I NATURALLY BOOST GLP-1??
The answer is YES!!!
Your body is designed to produce GLP-1—if you give it the right inputs. This is the power of food-as-medicine. Your gut is a hormone powerhouse. When nourished properly, it can produce GLP-1 naturally—no prescriptions required.
Here’s how you can support natural GLP-1 production:
- Eat foods rich in prebiotics and fiber to feed beneficial gut bacteria
- Prioritize protein at every meal to stimulate gut hormones, including GLP-1
- Incorporate healthy fats to help slow digestion and support hormone regulation
- Engage in resistance training and regular movement
- Reduce inflammation with targeted anti-inflammatory foods
- Manage stress and prioritize sleep
Foods That Naturally Support GLP-1 Production
Add these to your weekly rotation to help your body produce GLP-1 and improve gut hormone function:
Fiber-Rich, Prebiotic Foods
These feed your beneficial gut bacteria, supporting GLP-1 signaling:
- Oats
- Garlic
- Onions
- Leeks
- Asparagus
- Jerusalem artichokes
- Green bananas
- Chicory root
- Apples
- Barley
- Flaxseed
Non-Starchy Vegetables
These provide antioxidants and fiber to support digestion and reduce inflammation:
- Broccoli
- Kale
- Brussels sprouts
- Spinach
- Zucchini
- Cabbage
Healthy Fats
Slow gastric emptying and support hormonal balance:
- Avocados
- Extra virgin olive oil
- Nuts and seeds (chia, flax, almonds, walnuts)
- Fatty fish (salmon, sardines, mackerel)
Protein-Rich Foods
Help preserve lean muscle and stimulate GLP-1 release:
- Eggs (especially pasture-raised)
- Organic & grass fed poultry
- Grass-fed beef
- Wild-caught fish
- Lentils and legumes
- Greek yogurt (unsweetened, organic, grass fed)
- Plant-based protein (organic: tofu, tempeh, pea protein)
Fermented Foods
Support gut health and gut-brain signaling pathways:
- Sauerkraut
- Kimchi
- Kefir
- Plain yogurt (grass-fed, with live cultures)
- Miso
- Tempeh
Bonus Tip: Chewing slowly and mindfully can also increase GLP-1 secretion!
All of these foods are featured throughout Phil’s 30 Day REBOOT—with delicious recipes and flexible meal plans designed to reduce inflammation, support gut function, and naturally encourage GLP-1 production.
Meds Can Help. But Habits Heal
Here’s the heart of it all…
Medications like Ozempic can initiate change, but they don’t create lasting transformation. That comes from the habits you build and the relationship you cultivate with your food, your body, and your mindset.
If you’re currently using GLP-1 medication, or considering it, make sure you also:
- Prioritize muscle maintenance with protein and resistance training
- Use your renewed energy and focus to build real, sustainable habits
- View medication as a tool, not a solution
Why Phil’s 30 Day REBOOT Is the Perfect Partner
Whether you're on GLP-1 meds or not, Phil’s REBOOT offers a safe, supportive, and structured way to:
✅ Reset your metabolism
✅ Refuel with personalized, anti-inflammatory foods
✅ Rewire your relationship with food and health
It’s not about perfection. It’s about empowerment—and a path forward that actually works long-term.
GLP-1 is a powerful hormone—and understanding how it works can give you a major edge in your health journey. Whether you’re leveraging medication or going all-natural, you can reclaim your metabolism, reduce inflammation, and create a body that feels strong and supported.
You are not broken. Your body is asking for support—not punishment.
Let’s give it what it needs, one step at a time.